Actor Rob Lowe and his wife, jewelry designer Sheryl Lowe, have struck a deal to sell their East Coast-style estate in the affluent enclave of Montecito, Calif., for around $45.5 million, according to people familiar with the deal.

The deal is one of the priciest ever to close in the celebrity-studded community that has drawn the likes of Ellen DeGeneres and Oprah Winfrey.

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The buyers are retired health-care private-equity executive Jack McGinley and his wife Julie McGinley, those people said. In August, the McGinleys put their 10-acre Massachusetts estate designed by Robert A.M. Stern Architects on the market for $18.9 million, The Wall Street Journal reported. At the time, they said they were planning to spend more time in California.

The roughly 10,000-square-foot house was inspired by the architecture of the Virginia countryside, where Mr. Lowe spent time as a child.

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The Lowes’ property came on the market in 2018 for $47 million,The Wall Street Journal reported, but it does not appear to have been publicly listed at the time of the deal.

The roughly 10,000-square-foot house was inspired by the architecture of the Virginia countryside, where Mr. Lowe spent time as a child, the Journal reported. It has six bedrooms, formal living and dining areas, a home office, a screening room, a wine cellar and numerous terraces. There is also a piano bar, where Mr. Lowe, who has appeared in shows like "The West Wing," has been known to sing.

The property was built by the Lowes, who purchased the land in 2005, records show.

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The property also includes a guesthouse, a reflecting pool, a koi pond, rose and vegetable gardens, a swimming pool, a fire pit and a tennis court.

Mr. Lowe has recently appeared in the television shows "9-1-1: Lone Star" and "Parks and Recreation."

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